Nrbc 0.1/100 Wbc

4 min read Jun 26, 2024
Nrbc 0.1/100 Wbc

NRBC 0.1/100 WBC: Understanding the Significance of Nucleated Red Blood Cells

What are Nucleated Red Blood Cells (NRBCs)?

Nucleated Red Blood Cells, also known as Normoblasts, are immature red blood cells that still have a nucleus. Normally, red blood cells lose their nucleus as they mature and enter the bloodstream. However, in certain conditions, NRBCs can be present in the peripheral blood, which can be an indication of an underlying health issue.

What does NRBC 0.1/100 WBC mean?

A complete blood count (CBC) is a common laboratory test that measures various components of blood, including white blood cells (WBCs), red blood cells (RBCs), hemoglobin, and platelets. In the CBC report, NRBCs are usually reported as a percentage of total WBCs.

NRBC 0.1/100 WBC means that for every 100 white blood cells, there is 0.1 nucleated red blood cell present. This value is considered abnormal, as normally, NRBCs should not be present in the peripheral blood.

Causes of Elevated NRBCs

Several conditions can cause an increase in NRBCs, including:

Bone Marrow Disorders

  • Bone marrow failure or myelodysplastic syndrome
  • Leukemia, such as Acute Myeloid Leukemia (AML)
  • Myeloproliferative neoplasms, like Polycythemia Vera

Chronic Inflammation

  • Chronic infections, such as tuberculosis or endocarditis
  • Autoimmune disorders, like Rheumatoid Arthritis or Lupus
  • Chronic liver or kidney disease

Hematopoietic Stress

  • Severe anemia or bleeding
  • Hemolytic anemia
  • Sickle cell disease

Other Conditions

  • Cancer, such as lung or breast cancer
  • Infections, like sepsis or pneumonia
  • Inflammatory disorders, like Crohn's disease or ulcerative colitis

What does an Elevated NRBC Count Indicate?

An elevated NRBC count can be a sign of an underlying bone marrow disorder or a response to chronic inflammation. It may also indicate that the bone marrow is under stress, leading to the release of immature red blood cells into the circulation.

What to Do If You Have an Elevated NRBC Count?

If you have an elevated NRBC count, it is essential to consult with your doctor to determine the underlying cause. Your doctor may order additional tests, such as a bone marrow biopsy, to evaluate the bone marrow function and identify any potential disorders.


In conclusion, an NRBC count of 0.1/100 WBC is abnormal and may indicate an underlying health issue. It is essential to consult with a doctor to determine the cause and appropriate treatment.

Featured Posts