Trulicity 1.5 Mg/0.5 Ml Pen

4 min read Jun 26, 2024
Trulicity 1.5 Mg/0.5 Ml Pen

Trulicity 1.5 mg/0.5 mL Pen: A Comprehensive Overview


Trulicity 1.5 mg/0.5 mL Pen is a prescription medication used to treat type 2 diabetes in adults. It is a glucagon-like peptide-1 (GLP-1) receptor agonist, which helps to lower blood sugar levels and improve insulin secretion. In this article, we will delve into the details of Trulicity 1.5 mg/0.5 mL Pen, including its mechanism of action, dosage, benefits, and potential side effects.

Mechanism of Action

Trulicity 1.5 mg/0.5 mL Pen contains dulaglutide, a GLP-1 receptor agonist that works by:

  • Increasing insulin secretion: Dulaglutide stimulates the release of insulin from the pancreas, helping to lower blood sugar levels.
  • Inhibiting glucagon secretion: Dulaglutide reduces the production of glucagon, a hormone that raises blood sugar levels.
  • Slowing gastric emptying: Dulaglutide slows the emptying of the stomach, reducing the peak blood glucose levels after a meal.

Dosage and Administration

The recommended dose of Trulicity 1.5 mg/0.5 mL Pen is 1.5 mg injected subcutaneously once a week. The dose can be increased to 3.0 mg or 4.5 mg once a week if needed. Trulicity 1.5 mg/0.5 mL Pen is available in a single-dose pen injector, which contains a total of 0.5 mL of solution.


Trulicity 1.5 mg/0.5 mL Pen has been shown to:

  • Lower HbA1c levels: Trulicity 1.5 mg/0.5 mL Pen reduces HbA1c levels, a measure of average blood sugar control over the past 2-3 months.
  • Improve fasting plasma glucose: Trulicity 1.5 mg/0.5 mL Pen decreases fasting plasma glucose levels, a measure of blood sugar levels after an overnight fast.
  • Reduce body weight: Trulicity 1.5 mg/0.5 mL Pen can help with weight loss, which is a common complication of type 2 diabetes.

Side Effects

The most common side effects of Trulicity 1.5 mg/0.5 mL Pen include:

  • Nausea and vomiting
  • Diarrhea
  • Abdominal pain
  • Injection site reactions

Serious Side Effects

Trulicity 1.5 mg/0.5 mL Pen may cause more serious side effects, including:

  • Pancreatitis: Inflammation of the pancreas, which can be life-threatening if left untreated.
  • Thyroid C-cell tumors: An increased risk of thyroid C-cell tumors, such as medullary thyroid carcinoma.
  • Hypoglycemia: Low blood sugar levels, especially when used with other diabetes medications.


Trulicity 1.5 mg/0.5 mL Pen is a valuable treatment option for adults with type 2 diabetes. Its unique mechanism of action and once-weekly dosing make it a convenient and effective way to manage blood sugar levels. However, it is essential to carefully review the potential side effects and benefits with a healthcare provider before starting treatment.